From Wikipedia, the free encyclopedia
Inorganic chemistry is the branch of chemistry concerned with the properties and behavior of inorganic compounds. This field covers all chemical compounds except the myriad organic compounds (compounds containing C-H bonds), which are the subjects of organic chemistry. The distinction between the two disciplines is far from absolute, and there is much overlap, most importantly in the sub-discipline of organometallic chemistry.
Key concepts
The bulk of inorganic compounds occur as salts, the combination of cations and anions joined by ionic bonding. Examples of cations are sodium Na+, and magnesium Mg2+ and examples of anions are oxide O2− and chloride Cl−. As salts are neutrally charged, these ions form compounds such as sodium oxide Na2O or magnesium chloride MgCl2. The ions are described by their oxidation state and their ease of formation can be inferred from the ionization potential (for cations) or from the electron affinity (anions) of the parent elements.
Important classes of inorganic compounds are the oxides, the carbonates, the sulfates and the halides. Many inorganic compounds are characterized by high melting points. Inorganic salts typically are poor conductors in the solid state. Another important feature is their solubility in e.g. water (see: solubility chart), and ease of crystallization. Where some salts (e.g. NaCl) are very soluble in water, others (e.g. SiO2) are not.
The simplest inorganic reaction is double displacement when in mixing of two salts the ions are swapped without a change in oxidation state. In redox reactions one reactant, the oxidant, lowers its oxidation state and another reactant, the reductant, has its oxidation state increased. The net result is an exchange of electrons. Electron exchange can occur indirectly as well, e.g. in batteries, a key concept in electrochemistry.
When one reactant contains hydrogen atoms, a reaction can take place by exchanging protons in acid-base chemistry. In a more general definition, an acid can be any chemical species capable of binding to electron pairs is called a Lewis acid; conversely any molecule that tends to donate an electron pair is referred to as a Lewis base. As a refinement of acid-base interactions, the HSAB theory takes into account polarizability and size of ions.
Inorganic compounds are found in nature as minerals. Soil may contain iron sulfide as pyrite or calcium sulfate as gypsum. Inorganic compounds are also found multitasking as biomolecules: as electrolytes (sodium chloride), in energy storage (ATP) or in construction (the polyphosphate backbone in DNA).
The first important man-made inorganic compound was ammonium nitrite for soil fertilization through the Haber process. Inorganic compounds are synthesized for use as catalysts such as vanadium(V) oxide and titanium(III) chloride, or as reagents in organic chemistry such as lithium aluminium hydride.
Subdivisions of inorganic chemistry are organometallic chemistry, cluster chemistry and bioinorganic chemistry. These fields are active areas research in inorganic chemistry, aimed toward new catalysts, superconductors, and therapies.
Industrial inorganic chemistry
Inorganic chemistry is a highly practical area of science. Traditionally, the scale of a nation's economy could be evaluated by their productivity of sulfuric acid. The top 20 inorganic chemicals manufactured in Canada, China, Europe, Japan, and the US (2005 data):[1] aluminium sulfate, ammonia, ammonium nitrate, ammonium sulfate, carbon black, chlorine, hydrochloric acid, hydrogen, hydrogen peroxide, nitric acid, nitrogen, oxygen, phosphoric acid, sodium carbonate, sodium chlorate, sodium hydroxide, sodium silicate, sodium sulfate, sulfuric acid, and titanium dioxide,
Descriptive inorganic chemistry
Descriptive inorganic chemistry focuses on the classification of compounds based on their properties. Partly the classification focuses on the position in the periodic table of the heaviest element (the element with the highest atomic weight) in the compound, partly by grouping compounds by their structural similarities. When studying inorganic compounds, one often encounters parts of the different classes of inorganic chemistry (an organometallic compound is characterized by its coordination chemistry, and may show interesting solid state properties).
Different classifications are:
Coordination compounds
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- See also: Werner-type complex
Classical coordination compounds feature metals bound to "lone pairs" of electrons residing on the main group atoms of ligands such as H2O, NH3, Cl−, and CN−. In modern coordination compounds almost all organic and inorganic compounds can be used as ligands. The "metal" usually is a metal from the groups 3-13, as well as the trans-lanthanides and trans-actinides, but from a certain perspective, all chemical compounds can be described as coordination complexes.
The stereochemistry of coordination complexes can be quite rich, as hinted at by Werner's separation of two enantiomers of [Co((OH)2Co(NH3)4)3]6+, an early demonstration that chirality is not inherent to organic compounds. A topical theme within this specialization is supramolecular coordination chemistry.[2]
Main group compounds
These species feature elements from groups 1, 2 and 13-18 (excluding hydrogen) of the periodic table. Due to their often similar reactivity, the elements in group 3 (Sc, Y, and La) and group 12 (Zn, Cd, and Hg) are also generally included.[3]
Main group compounds have been known since the beginnings of chemistry, e.g. elemental sulfur and the distillable white phosphorus. Experiments on oxygen, O2, by Lavoisier and Priestley not only identified an important diatomic gas, but opened the way for describing compounds and reactions according to stoichiometric ratios. The discovery of a practical synthesis of ammonia using iron catalysts by Carl Bosch and Fritz Haber in the early 1900’s deeply impacted mankind, demonstrating the significance of inorganic chemical synthesis. Typical main group compounds are SiO2, SnCl4, and N2O. Many main group compounds can also be classed as “organometallic”, as they contain organic groups, e.g. B(CH3)3). Main group compounds also occur in nature, e.g. phosphate in DNA, and therefore may be classed as bioinorganic. Conversely, organic compounds lacking (many) hydrogen ligands can be classed as “inorganic”, such as the fullerenes, buckytubes and binary carbon oxides.
Transition metal compounds
Compounds containing metals from group 4 to 11 are considered transition metal compounds. Compounds with a metal from group 3 or 12 are sometimes also incorporated into this group, but also often classified as main group compounds.
Transition metal compounds show a rich coordination chemistry, varying from tetrahedral for titanium (e.g. TiCl4) to square planar for some nickel complexes to octahedral for coordination complexes of cobalt. A range of transition metals can be found in biologically important compounds, such as iron in hemoglobin.
Organometallic compounds
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Usually, organometallic compounds are considered to contain the M-C-H group.[4] The metal (M) in these species can either be a main group element or a transition metal. Operationally, the definition of an organometallic compound is more relaxed to include also highly lipophilic complexes such as metal carbonyls and even metal alkoxides.
Organometallic compounds are mainly considered a special category because organic ligands are often sensitive to hydrolysis or oxidation, necessitating that organometallic chemistry employs more specialized preparative methods than was traditional in Werner-type complexes. Synthetic methodology, especially the ability to manipulate complexes in solvents of low coordinating power, enabled the exploration of very weakly coordinating ligands such as hydrocarbons, H2, and N2. Because the ligands are petrochemicals in some sense, the area of organometallic chemistry has greatly benefited from its relevance to industry.
Cluster compounds
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Clusters can be found in all classes of chemical compounds. According to the commonly accepted definition, a cluster consists minimally of a triangular set of atoms that are directly bonded to each other. But metal-metal bonded dimetallic complexes are highly relevant to the area. Clusters occur in "pure" inorganic systems, organometallic chemistry, main group chemistry, and bioinorganic chemistry. The distinction between very large clusters and bulk solids is increasingly blurred. This interface is the chemical basis of nanoscience or nanotechnology and specifically arise from the study of quantum size effects in cadmium selenide clusters. Thus, large clusters can be described as an array of bound atoms intermediate in character between a molecule and a solid.
Bioinorganic compounds
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See also Bioorganometallic chemistry
These compounds occur (by definition) in nature, but the subfield includes anthropogenic species, such as pollutants and drugs, e.g. Cisplatin.[5] The field includes many compounds, e.g. the phosphates in DNA, but also metal complexes containing ligands that range from biological macromolecules, commonly peptides, to ill-defined species such as humic acid, and to water (e.g. coordinated to gadolinium complexes employed for MRI).
Solid state compounds
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This important area focuses on structure,[6] bonding, and the physical properties of materials. In practice, solid state inorganic chemistry uses techniques such as crystallography to gain an understanding of the properties that result from collective interactions between the subunits of the solid. Included in solid state chemistry are metals and their alloys or intermetallic derivatives. Related fields are condensed matter physics, mineralogy, and materials science.
Theoretical inorganic chemistry
An alternative perspective on the area of inorganic chemistry begins with the Bohr model of the atom and, using the tools and models of theoretical chemistry and computational chemistry, expands into bonding in simple and then more complex molecules. Precise quantum mechanical descriptions for multielectron species, the province of inorganic chemistry, is difficult. This challenge has spawned many semi-quantitative or semi-empirical approaches including molecular orbital theory and ligand field theory, In parallel with these theoretical descriptions, approximate methodologies are employed, including density functional theory.
Exceptions to theories, qualitative and quantitative, are extremely important in the development of the field. For example, CuII2(OAc)4(H2O)2 is almost diamagnetic below room temperature whereas Crystal Field Theory predicts that the molecule would have two unpaired electrons. The disagreement between qualitative theory (paramagnetic) and observation (diamagnetic) led to the development of models for "magnetic coupling." These improved models led to the development of new magnetic materials and new technologies.
Qualitative theories
Inorganic chemistry has greatly benefited from qualitative theories. Such theories are easier to learn as they require little background in quantum theory. Within main group compounds, VSEPR theory powerfully predicts, or at least rationalizes, the structures of main group compounds, such as an explanation for why NH3 is pyramidal whereas ClF3 is T-shaped. For the transition metals, crystal field theory allows one to understand the magnetism of many simple complexes, such as why [FeIII(CN)6]3− has only one unpaired electron, whereas [FeIII(H2O)6]3+ has five. A particularly powerful qualitative approach to assessing the structure and reactivity begins with classifying molecules according to electron counting, focusing on the numbers of valence electrons, usually at the central atom in a molecule.
Group Theory
A central construct in inorganic chemistry is Group Theory.[7] Group Theory provides the language to describe the shapes of molecules according to their "point group symmetry". Group Theory also enables factoring and simplification of theoretical calculations.
Spectroscopic features are analyzed and described with respect to the symmetry properties of the, inter alia, vibrational or electronic states. Knowledge of the symmetry properties of the ground and excited states allows one to predict the numbers and intensities of absorptions in vibrational and electronic spectra. A classic application of Group Theory i
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![Crystal field theory explains why [FeIII(CN)6]3− has only one unpaired electron](http://www.wikipedia.org/wiki/Image:Ferricyanide-3D.png)
